Cystic Fibrosis Liver Disease: Signs and Symptoms


What are the signs and symptoms of cystic fibrosis liver disease?

CF patients with mild liver problems usually do not have any symptoms. In patients with advanced CFLD, an enlarged spleen or liver is the most common finding. As the advanced CFLD progresses, high pressure in the portal vein, the large vein that brings blood to the liver develops (portal hypertension). This can lead to accumulation of fluid in the abdomen and bleeding from dilated veins (called varices) in the esophagus or stomach. In some patients, poor nutrition can also develop as a result of CFLD.