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Diphenhydramine (Benadryl) Dose Table

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Diphenhydramine (Benadryl) Dose Table
Child's weight (pounds)20-2425-3738-4950-99100+lbs.
Liquid 12.5 mg/ 1 teaspoon (tsp)¾12--tsp
Liquid 12.5 mg/5 milliliters (ml)457.510--ml
Chewable 12.5 mg--124tablets
Tablets 25 mg--½½12tablets
Capsules 25 mg------12caps

When to Use. Treatment of allergic reactions, nasal allergies, hives and itching.

Table Notes:

  • AGE LIMITS. For allergies, don't use under 1 year of age. (Reason: it causes most babies to be sleepy). For colds, not advised at any age. (Reason: no proven benefits). They should be not be given if under 4 years old. If under 6 years, don't give products with more than one ingredient in them. (Reason: FDA recommendations 10/2008).
  • DOSE. Find the child's weight in the top row of the dose table. Look below the correct weight for the dose based on the product you have.
  • MEASURE the DOSE. Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medicine.  If not, you can get a med syringe at drug stores. If you use a teaspoon, it should be a measuring spoon. (Reason: regular spoons are not reliable.) Keep in mind 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.  
  • ADULT DOSE. 50 mg
  • HOW OFTEN. Repeat every 6 hours as needed.
  • CHILDREN’S BENADRYL FASTMELTS. Each fastmelt tablet equals 12.5 mg. They are dosed the same as chewable tablets.