Children's Hospital Colorado
Pediatric Surgery

Familial Adenomatous Polyposis (FAP)

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What is familial adenomatous polyposis?

Familial adenomatous polyposis (FAP) is a rare genetic condition that causes polyps (growths) in the gastrointestinal tract (intestine and colon). These polyps, called “adenomas,” begin in early childhood. If the polyps are not treated, they can lead to colon cancer.

What causes familial adenomatous polyposis?

FAP is a genetic condition that is usually passed down through families. About 25% of people who have FAP do not have a family history of the disease. The condition can also be associated with genetic syndromes such as Gardner’s syndrome and Turcot syndrome. FAP occurs in approximately 1 in 10,000 people. Males and females are affected equally.

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