Children's Hospital Colorado
Craniofacial Center

Saethre-Chotzen Syndrome

We see more, treat more and heal more kids than any other hospital in the region.

U.S. News & World Report Honor Roll 2021-2 Badge

Get Care

Would you like to learn more about us?
Craniofacial Center
Do you have questions about your child’s condition?
Call

What is Saethre-Chotzen syndrome?

Saethre-Chotzen syndrome is a condition characterized by abnormalities of the skull and midface. Patients with Saethre-Chotzen syndrome may also have cleft palate and/or short and webbed fingers and toes.

Who gets Saethre-Chotzen syndrome?

Saethre-Chotzen syndrome is a rare congenital condition that occurs in 1 of 25,000 to 50,000 newborn babies with a 1:1 male to female ratio. It can be inherited in an autosomal dominant fashion from a parent with Saethre-Chotzen syndrome, or be due to a fresh genetic mutation. A parent with Saethre-Chotzen syndrome has a 50% chance of passing the condition to a child. The mutation occurs on a gene called TWIST1.

Next steps

Get to know our pediatric experts.

Kassie Montgomery, CPNP-PC

Kassie Montgomery, CPNP-PC

Certified Pediatric Nurse Practitioner

Patient ratings and reviews are not available Why?

Mark Greyson, MD

Mark Greyson, MD

Hand Surgery, Plastic & Reconstructive Surgery, Surgery

Patient ratings and reviews are not available Why?

Michael Handler, MD

Michael Handler, MD

Neurosurgery, Neurosurgery - Pediatric

David Campbell, MD

David Campbell, MD

Cardiac Surgery, Thoracic Surgery

Patient ratings and reviews are not available Why?