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It's our goal to deliver timely, accurate test results and provide the insight and expertise you need to formulate optimal treatment plans and obtain better patient outcomes.
In addition to fulfilling requisitions for our patients at Children's Hospital Colorado, our state-of-the-art labs provide reference services for doctors around the world.
As a partner in patient care, our hospital and the Department of Pathology and Laboratory Services offer valuable tools and resources to support and elevate referring physicians' practice.
Our laboratory specialists have compiled instructions, guidelines and resources for providers requesting a lab requisition from the Children's Colorado labs.
Browse our downloadable lab requisition forms and general and special collection instructions.
In our Laboratory Test Directory, referring providers can find everything they need to submit a specimen and/or requisition to our laboratories, including:
"Whether we're calling referring providers with a critical patient's preliminary results or optimizing ordering processes, we're committed to developing and maintaining strong relationships with these partners and getting their patients the highest quality test results in the shortest amount of time."
— Amy Treece, MD
Our partnership with the University of Colorado School of Medicine, home to one of the best departments of pediatrics in the nation, according to U.S. News & World Report, enables us to offer ongoing continuing education opportunities.
Our laboratory facilities at the Department of Pathology and Laboratory Services are accredited by:
View our laboratory certificates and licenses and learn more about our accreditation.
For over a decade, U.S. News & World Report has ranked our hospital as one of the best children's hospitals in the nation, and for eight years in a row, Children's Colorado has been the consistent choice of local physicians for the care of their loved ones.
By tracking, measuring and reporting on outcomes, patient experience, and quality and safety measures, we're able to continually improve the safety and quality of the care we provide. As we continually improve our laboratory services and operations, we uphold excellence in pathology and laboratory medicine.
Read more about Quality & Patient Safety at Children's Colorado.
Our clinical, pathological and genetic laboratories provide local, regional and national physicians with a full range of diagnostic services that inform their patient care.
The Core Laboratory at Children's Colorado offers general and specialized laboratory testing on blood, body fluids and urine 24 hours a day, 7 days a week.
The Core Laboratory consists of chemistry, hematology, coagulation and urinalysis.
Top diagnostic tests performed in the Core Lab include:
The Chemistry Laboratory performs a wide variety of tests on a STAT and routine basis. The lab can provide results for most general chemistry tests within one hour of receipt, while other tests are batched and tested daily.
Our test menu includes: electrolytes, enzymes, proteins, lipids, therapeutic drug monitoring (TDM), endocrinology and hormone tests.
Our laboratory is accredited by the Cystic Fibrosis Foundation to collect and analyze sweat for patients to rule-out or confirm a diagnosis of cystic fibrosis (CF). As a center for pharmaceutical research, our section has been integral in the development and approval of new drugs to treat CF.
The Chemistry Laboratory also helps the Inherited Metabolic Disease Clinic in the diagnosis and follow-up care for patients with phenylketonuria (PKU). We perform regular phenylalanine/tyrosine testing on children and pregnant mothers with this inherited disorder with our mass spectrophotometer.
The Hematology Laboratory performs clinical laboratory services 24/7 and can provide vital hematology test results within one hour of sample receipt.
Our Hematology Laboratory supports the Hemophilia and Thrombosis Center with a full menu of coagulation testing including:
The Children's Colorado point-of-care (POC) team ensures that all of the more than 1,500 nurses, providers and other clinical care team members performing POC testing are meeting or exceeding quality and patient safety requirements.
Most common POC tests:
If you have any questions on POC testing, contact the POC team by phone at 720-777-6717 or by email at firstname.lastname@example.org.
The Blood Bank Laboratory is accredited by multiple regulatory agencies including the American Association of Blood Banks (AABB).
The Blood Bank performs patient testing and provides blood products, such as platelets, plasma and red blood cells, to all areas of Children's Colorado.
Blood products are prepared for all types of transfusions, including: traumas, scheduled surgeries, maternal intrauterine transfusions, sickle cell patients, oncology/BMT patients and other chronically transfused patients.
The Blood Bank Laboratory works closely with the Blood Donor Center to ensure the supply is always sufficient to meet the needs for all patients. Furthermore, as a level one trauma center for a seven-state region, the Blood Bank Laboratory is prepared for mass-casualty emergencies.
Commonly ordered blood tests include:
The Blood and Marrow Transplant Laboratory team is involved in novel cellular therapy research and clinical trials.
Top commonly ordered tests:
Utilizing culture, antigen detection, serology and molecular methods, The Department of Pathology and Laboratory Services’ Microbiology/Virology Laboratory diagnoses infections caused by:
Working closely with other teams throughout the hospital and the clinical laboratory – like the Infectious Disease, Antimicrobial Stewardship and Pharmacy teams – this lab aids in the diagnosis of infectious diseases.
We also support outbreak management initiatives in collaboration with both the Colorado Department of Public Health and Environment and the Centers for Disease Control and Prevention.
With state-of-the-art instruments and assays, we're able to provide critical, specialized services, including:
The Microbiology Lab is involved in teaching initiatives and welcomes:
For further information on learning opportunities, speak with your institution or visit American Society for Microbiology.
The Anatomic Pathology Laboratory at Children's Colorado provides an array of laboratory services, including:
Surgical pathology procedures: Our lab performs gross examination of surgical specimens with or without microscopic examination.
Cytology services: Cytology services include histologic examination of body fluids, adequacy assessment and processing of fine-needle aspirates. Cell-block and cytospin preparation is also available for analysis of liquid specimens.
Autopsy services: The Anatomic Pathology Lab provides post-mortem examination of deceased patients as ordered, as part of the hospital's quality initiative and to support our educational mission. Autopsy consultations are also performed for a fee, mostly originating from local hospitals, and also occasionally from local medical examiner jurisdictions.
Histological services: We offer a full range of histological services for routine and research specimens. Using state-of-the-art technology, our histologists provide and support comprehensive diagnostic services to clinicians, hospitals and outside laboratories. As specially trained pediatric experts, we are uniquely positioned to support the diagnosis and care of pediatric patients.
Our dedication to providing high-quality histology services with affordable, competitive pricing and rapid turn-around times makes ours one of the most reliable sources for histology services in our region.
Flow cytometry: Our laboratory supports the Center for Cancer and Blood Disorders by offering a full range of immunophenotyping services and diagnostic testing for routine and research specimens.
Routinely available surface marker panels include:
Our Electron Microscopy Laboratory provides local, regional and national clients with a full range of diagnostic services for both adult and pediatric patients.
Our high-volume facility specializes in diagnostic ultrastructural pathology and is dedicated to quick delivery of a quality product (normally within 24 hours of specimen receipt).
The laboratory is equipped with two modern transmission electron microscopes, a JEOL JEM-1400Plus and a Hitachi H-7650, as well as a scanning electron microscope (a JEOL JSM-6010LA).
Specialized laboratory services
In addition to conventional electron microscopy, we also offer specialized diagnostic techniques such as:
We provide technical only or complete professional services. The technical service option offers informal interpretive assistance with specimen viewing via telepathology possible. A HIPAA-compliant, web-based delivery system enables instantaneous result distribution. Pathologist interpretation is available on a fee-for-service basis, if requested.
Specimen submission requirements
Please submit tissue for conventional transmission electron microscopic examination, energy dispersive x-ray spectroscopy and most scanning electron microscopic applications in glutaraldehyde fixative.
If glutaraldehyde fixative is unavailable, please submit in a formaldehyde fixed wet tissue. Depending upon circumstances, a paraffin embedded tissue or frozen tissue that has been allowed to thaw in chilled fixative will be accepted. Ship blood, unfixed, via an overnight express carrier. You do not need to place hair specimens for scanning electron microscopic examination in fixative.
The Electron Microscopy Lab also provides fixative and express shipping upon request. Specimens must be shipped with the correct electron microscopy request forms (below). Our receiving is available 24 hours a day, as well as throughout weekends and holidays.
Contact the Electron Microscopy Lab
Please contact us for additional technical information, advice on specimen handling or for pricing information.
Ship specimens to
Department of Pathology and Laboratory Medicine
Electron Microscopy Laboratory
Children’s Hospital Colorado
13123 East 16th Avenue
Aurora, CO 80045
The Biochemical Genetics Laboratory provides laboratory services for a variety of institutions throughout the country and around the world.
Our comprehensive test list allows us to provide clinical testing to diagnose and monitor treatment of many inherited metabolic disorders, such as amino acid, organic acid and fatty acid oxidation disorders.
Most commonly ordered labs for genetic testing include:
With unmatched capabilities, our Biochemical Genetics Lab is the only laboratory in the country to perform:
While our lab offers TMAu testing, an authorized provider with a state issued NPI number must order this testing. Please review the collection and handling instructions for TMA samples (.pdf) before sending in samples. If there are questions regarding testing for TMAu, please have the authorized provider contact us at LabClientServices@childrenscolorado.org or 720-777-6711.
Browse our downloadable lab requisition forms and collection instructions for our Biochemical Genetics Lab.
At Precision Diagnostics, our laboratory team provides molecular diagnostic and genetic testing. This laboratory was formed through a joining of the Denver Genetics Laboratory and the Molecular Diagnostics Laboratory to create a comprehensive molecular laboratory focused on all areas of molecular precision diagnostics. Our capabilities also cover the testing and identification of:
Our molecular laboratory's resources and capabilities include next-generation sequencing (NGS), Sanger sequencing, targeted array, comparative genomic hybridization (CGH), triplet repeat primed polymerase chain reaction (PCR), bone marrow transplantation and engraftment monitoring.
Browse our downloadable lab requisition forms and collection instructions for our Precision Diagnostics Lab.
Our Mitochondrial Laboratory provides diagnostic testing for respiratory chain enzyme diseases. We perform spectrophotometric respiratory chain enzyme assays in all tissues and have additional testing capabilities, such as blue native PAGE analyses.
Services offered in the Mitochondrial Lab include:
Browse our downloadable lab requisition forms and collection instructions for our Mitochondrial Laboratory.
For health professionals interested in sending us a specimen or in need of more information about our test menu, please contact our Lab Outreach Coordinator via email at LabOutreach@childrenscolorado.org or by phone at 720-777-2723.
For all other questions, please contact Lab Client Services by email or by phone at 720-777-6711.