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The Electron Microscopy (EM) Laboratory at Children’s Hospital Colorado has provided local, regional and national clients with a full range of diagnostic services for both adult and pediatric patients since 1968. The high-volume facility specializes in diagnostic ultrastructural pathology and is dedicated to quick delivery of a quality product (normally within 24 hours of specimen receipt).
Our EM lab team, which includes Scientific Director Gary Mierau, PhD, Medical Direct Dr. Mark Lovell and four full-time electron microscopists, have more than 100 years of combined experience, including experience with renal, respiratory (including ciliopathies), muscular, metabolic, hepatocytic, neoplastic and infectious, and other disease processes. They have authored more than a hundred scientific articles, reviews, book chapters and books on ultrastructural pathology and lectured in more than a dozen countries.
The laboratory is equipped with two modern transmission electron microscopes. (A JEOL JEM-1400Plus and a Hitachi H-7650) and a scanning electron microscope (JEOL JSM-6010LA).
In addition to conventional electron microscopy, we also offer specialized diagnostic techniques such as:
We provide technical only or complete professional services. The technical service option offers informal interpretive assistance, with specimen viewing via telepathology possible. A HIPAA-compliant, web-based delivery system enables instantaneous result distribution. Pathologist interpretation is available on a fee-for-service basis, if requested.
Please submit tissue for conventional transmission electron microscopic examination, energy dispersive x-ray spectroscopy and most scanning electron microscopic applications in glutaraldehyde fixative.
If glutaraldehyde fixative is unavailable, please submit in a formaldehyde fixed wet tissue. Depending upon circumstances, a paraffin embedded tissue or frozen tissue that has been allowed to thaw in chilled fixative will be accepted. Ship blood, unfixed, via an overnight express carrier. You do not need to place hair specimens for scanning electron microscopic examination in fixative.
The EM lab also provides fixative and express shipping upon request. Specimens must be shipped with the correct Electron Microscopy Request forms (below). Our receiving is available 24 hours a day as well as throughout weekends and holidays.
Please email us for additional technical information, advice with respect to specimen handling or for pricing information. We can also be reached Monday-Friday: 6:00 a.m.-5:30 p.m.(MT) at:
Electron Microscopy Lab