My research focuses on a specific type of cancer called high-grade glioma, an aggressive brain tumor affecting both children and adults. We focus especially on two pediatric subtypes called diffuse intrinsic pontine glioma and pediatric glioblastoma. I work in the lab to find new treatments for these tumors; we then study the treatments in laboratory models of the tumors, including mouse models, and then bring the treatments most likely to be successful to clinical trials in children.
For Referring Providers:
My research focuses on novel targets and therapies for pediatric high-grade glioma, including diffuse intrinsic pontine glioma, and by extension, adult high-grade glioma as well. In my lab, we work to discover and exploit innovative, rational targets in these tumors, and to bring novel treatments against these targets through laboratory models of these diseases to early-phase clinical trials.