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Research & Innovation
It starts with a Q:
For the latest cutting-edge research, innovative collaborations and remarkable discoveries in child health, read stories from across all our areas of study in Q: Advances and Answers in Pediatric Health.
Clinical Pathways
What are Clinical Pathways?
Clinical pathways assist clinicians in standardizing the evaluation, diagnosis, and care of patients with specific conditions, with the goal of achieving optimal outcomes. They translate national guidelines and the best available evidence for clinical application into local context. Clinical pathways are used to inform decision-making at the point of care, to train new clinicians on evidence-based practice, and to support continuous improvement.1
If you want to learn more about clinical pathways, please contact Katie Sellinghausen.
- Rotter T, Kinsman L, James EL, et al. Clinical pathways: effects on professional practice, patient outcomes, length of stay and hospital costs. Cochrane Database of Systematic Reviews. 2010(3). DOI: 10.1002/14651858.CD006632.pub2.
Clinical Pathways, A to Z
Please visit Children's Hospital Colorado on AgileMD for pathways and clinical guidance.
Note: Use the Google Chrome browser to access AgileMD.
A
Acetaminophen (APAP) Toxicity.pdf
January 24, 2025
Acute Abnormal Uterine Bleeding (AUB)
June 09, 2022
Acute Chest Syndrome
January 17, 2023
Acute Pancreatitis - Nutrition
March 27, 2025
Anaphylaxis
September 11, 2019
Antibiotic Durations Quick Reference Table
July 07, 2023
Asthma Exacerbation Management Clinical Pathway
August 22, 2023
Asthma Outpatient Management: Primary Care (PCN/CHCO)
August 22, 2023
Pediatric Acute Painful Scrotum Clinical Pathway
February 24, 2022
Pediatric Appendicitis Clinical Pathways
June 18, 2021
B
Bariatric Surgery Inpatient
November 21, 2024
Buprenorphine Induction for Opioid Use Disorder
March 04, 2024
Button Battery, Ingested
April 04, 2025
Pediatric Bronchiolitis Clinical Pathways
October 28, 2021
C
Clostridioides Difficile (C. diff)
March 26, 2024
Community Acquired Pneumonia (CAP), Uncomplicated Clinical Pathway
September 01, 2021
Concussion Clinical Pathway
May 07, 2024
Croup
October 26, 2021
High Risk Cerebral Palsy (for VDRO Surgery)
October 26, 2021
Infant with Cleft Lip and/or Cleft Palate
March 27, 2025
D
Aspiration and Dysphagia in Children with Down Syndrome
June 24, 2021
Diabetic Ketoacidosis (DKA)
March 28, 2022
Diagnostic Time Out Algorithm
September 17, 2024
E
Emergency Department/Urgent Care Constipation
June 24, 2021
Emergency Department/Urgent Care Gastroenteritis
June 24, 2021
EVALI Clinical Pathway
May 04, 2022
F
Fever in Infants 0 to 60 Days
December 16, 2022
Fracture, Buckle
March 27, 2025
Fracture, Femoral Shaft
February 13, 2025
Fracture, Supracondylar Humerus
February 26, 2024
H
Headache
June 24, 2021
Hemophilia & von Willebrand Disease Emergencies
June 24, 2021
I
Infantile Spasms
October 26, 2021
Intravenous Fluid Therapy
June 24, 2021
L
Leukapharesis for Hyperleukocytosis in Acute Leukemia.pdf
December 19, 2024
Lifestyle Medicine Ambulatory Clinical Pathways
July 27, 2023
M
Musculoskeletal Infection Clinical Pathway
June 21, 2023
Pediatric Migraine Clinical Pathways
September 29, 2021
N
Inhaled Nitric Oxide (iNO) Weaning in the CICU
June 24, 2021
Neonatal Hyperammonemia
September 30, 2022
Nephrotoxic Acute Kidney Injury (NAKI) Clinical Pathway
March 19, 2025
O
Opioid Prescribing Practices
June 24, 2021
Ovarian Torsion Clinical Pathway
January 05, 2023
Overweight and Obesity
June 24, 2021
Oxygen Weaning in the Premature Infant
June 24, 2021
P
Acute Pancreatitis
January 27, 2025
Community Acquired Pneumonia (CAP), Complicated
June 24, 2021
Penicillin Allergy Delabeling
June 24, 2021
Pneumothorax
April 14, 2025
Post Cardiac Arrest
June 26, 2021
Protein Energy Malnutrition
January 04, 2023
S
Neonatal Seizures after Acquired Brain Injury
June 24, 2021
Seizure, New Onset
June 24, 2021
Sepsis
June 14, 2024
Sepsis and Kids English
October 27, 2020
Sepsis and Kids Spanish
October 27, 2020
Sickle Cell Disease Management Clinical Pathway
June 21, 2023
Skin and Soft Tissue Infection
February 10, 2025
Spinal Fusion, High Risk
August 09, 2022
Spinal Fusion, Low Risk
June 30, 2021
Status Epilepticus
June 26, 2021
Stroke, Pediatric Arterial Ischemic (AIS)
June 24, 2021
T
Traumatic Brain Injury (TBI): Moderate/Severe
February 26, 2024
U
Undescended Testicle
January 27, 2025
Urinary Tract Infection (UTI)
November 06, 2024
Urolithiasis
November 15, 2022
V
Venous Thromboembolism (VTE) Prevention
July 22, 2021
Vitamin D Deficiency
November 11, 2021
W
Wound Vacuum Assisted Closure
June 24, 2021
Are there other clinical pathways that would be helpful to you in your practice? If so, let us know.
Firstline - antimicrobial stewardship guidance
Children's Hospital Colorado has implemented Firstline as a statewide resource for antimicrobial stewardship in Colorado. Firstline provides healthcare workers with local clinical pathways, antimicrobial formulary and dosing recommendations, pathogen information, and clinical tools. Visit Firstline for Children's Hospital Colorado for more information.