Children's Hospital Colorado

Researching the Developmental Origins of Health and Disease

A headshot of Lee Niswander, PhD.

About our research program at Children's Hospital Colorado

The Developmental Origins of Health and Disease research group provides insight into the underlying causes of human birth defects and childhood diseases through basic scientific research. Current areas of research emphasis focus on understanding the normal developmental processes that regulate the formation of the spinal cord and brain, muscles, lungs and limbs. Moreover, these research groups are creating mouse and zebrafish models of genetic defects to determine why these developmental processes go awry in children born with birth defects (such as spina bifida) or, for instance, who later develop neuromuscular deficits.

The ultimate goal is to strive to develop new cures and treatments for pediatric disorders and diseases through research into fundamental biological mechanisms. The research heads are also strongly dedicated to training and science education.

Program leader

Lee Niswander, PhD
Investigator, Howard Hughes Medical Institute
Professor, University of Colorado
Department of Pediatrics, Section of Developmental Biology
Children's Hospital Colorado

Program contact information

Claire Tsai
Administrative Assistant