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The completion of the Human Genome Project in 2003 inaugurated the era of sequence-based medicine, known initially as Genomic Medicine and, more recently, as Personalized Medicine. Whereas, the second half of the 20th century was a time when populations were examined using the tools of epidemiology, we now have the tools to investigate the characteristics of individuals within populations.
The ability to sequence an individual’s DNA will allow us to identify that child’s predisposition to disorders, including co-morbidities associated with his/her underlying condition, and adverse drug reactions associated with specific medications.
We anticipate that within the next decade, genomic sequencing will be a part of routine clinical laboratory assessment for children at Children's Hospital Colorado. Researchers in the Genomics Emphasis Area are creating the knowledge-base for Personalized Medicine.