Articles and Trials

• Urology
• May 01, 2023

A study of vincristine (VCR), commonly used in childhood cancer treatment, found sex-specific impacts to lower urinary tract function in mouse models, suggesting the risk of a potential side effect in childhood cancer survivors.

• Neonatology
• March 29, 2023

Researchers explore delayed cord clamping (DCC) benefits for term and preterm infants, finding improved survival and reduced complications. DCC implementation varies, but evidence supports benefits for historically excluded populations.

• Surgery
• March 07, 2023

Examining opioid and non-opioid analgesics before, during and after urology surgery for spinal bifida patients revealed significant differences between the two groups, with much greater use of non-opioid adjuncts and decreased opioid use in the group who received regional catheters.

• Oncology and Hematology
• February 24, 2023

Pre-clinical study results demonstrate the potential use of venetoclax combined with radiation therapy for pediatric diffuse midline glioma and warrants a phase 1b clinical trial.

• Pulmonary Medicine
• February 21, 2023

This study provides more knowledge into the role of lower airway inflammation in the development of primary ciliary dyskinesia lung disease.

• Multidisciplinary Child Health Research and Discoveries
• January 31, 2023

As a leader in pediatric intensive care with a focus on collaboration and innovation, our PICU team at Children's Hospital Colorado knew how to approach a severe case of COVID-19 in a 15-year-old girl.

• COVID-19 Research
• January 31, 2023

In a recent retrospective cohort analysis, researchers uncovered the disproportional impact that COVID-19 has had on racial and ethnic disparities in pediatric healthcare.

• Maternal and Fetal Medicine
• January 30, 2023

A new study explores the benefits of combining MRI scans with a quantitative risk scale to help confirm serious placenta conditions, which will help pregnant patients make more informed decisions and better equip care teams when creating treatment plans.

• Oncology and Hematology
• January 30, 2023

When a 2-year-old girl was diagnosed with multicentric carpotarsal osteolysis, or MCTO, doctors led a multidisciplinary effort to slow its progression and advance the research of this rare genetic disease.

• Heart
• January 30, 2023

Children with multisystem smooth muscle dysfunction syndrome, or MSMDS, who undergo anesthesia are prone to dangerous blood pressure drops. But a tailored, multidisciplinary approach to congenital heart disease can help improve surgical outcomes.

• Endocrinology
• January 30, 2023

Closed-loop pancreas systems are revolutionizing Type 1 diabetes management with outstanding glucose control and insulin delivery. In this article, Paul Wadwa, MD, shares the encouraging results from a 13-week trial with the Beta Bionics iLet® Bionic Pancreas.

• Gastroenterology and GI Surgery
• January 27, 2023

• Pulmonary Medicine
• January 27, 2023

In this research summary, researchers find evidence supporting the use of nintedanib for treating pulmonary fibrosis due to childhood interstitial lung disease.