Articles and Trials

• Neonatology
• October 11, 2022

Acetaminophen is often used in neonatal intensive care units to treat newborns with patent ductus arteriosus. But given its impact on the liver, researchers at Children’s Hospital Colorado investigated how it affects premature lungs.

• Oncology and Hematology
• October 11, 2022

For years, doctors have faced a difficult challenge in treating a subtype of B-cell acute lymphoblastic leukemia, which is known to change to acute myeloid leukemia –– easily evading CAR T-cells and significantly limiting treatment options.

• Neonatology
• October 11, 2022

The Colorado Fetal Care Center at Children’s Hospital Colorado achieves some of the best survival rates for the most severe cases of congenital diaphragmatic hernia –– thanks to early therapeutic repair on extracorporeal membrane oxygenation.

• Cardiology and Cardiothoracic Surgery
• October 10, 2022

Children’s Hospital Colorado was the first pediatric hospital to use the recently FDA-approved 3D intracardiac echocardiography (ICE) catheter from Phillips. With superior, high-resolution imaging, 3D ICE allows cardiac interventionalists to better navigate complex cardiac procedures without any significant additional time, risk or access points.

• Surgery
• October 10, 2022

Researchers from the largest volume center for pediatric living-donor liver transplants found that offering living donations at a high-volume transplant center can reduce time on the waiting list and improve outcomes.

• COVID-19 Research
• October 10, 2022

A consortium of researchers across multiple institutions explored the link between the COVID-19 pandemic and an unprecedented rise in Type 2 diabetes in children.

• Surgery
• October 03, 2022

Researchers reviewed data from children who had liver transplant for two types of liver tumors: hepatoblastoma and hepatocellular carcinoma. Despite varying outcomes, the data support liver transplantation to treat advanced tumors.

• September 30, 2022

Researchers defined anti-Ro/SSA antibody thresholds that can accurately identify pregnancies unlikely to develop fetal atrioventricular block, thereby reducing the need for costly and time-consuming ongoing fetal echo surveillance in pregnant patients.

• Oncology and Hematology
• September 21, 2022

Cancer and its treatment can often delay life experiences, but access to psychosexual care during and after cancer treatment is important for improving cancer survivors’ wellbeing.

• September 13, 2022

Diffuse midline glioma, a pediatric brainstem tumor, is almost always fatal. But for a small percentage of patients that have a NTRK gene mutation, TRK inhibition may provide clinical effectiveness.

• Maternal and Fetal Medicine
• September 13, 2022

In this study, in utero fetal treatment with steroids for atrioventricular block, a manifestation of fibrosis due to inflamed fetal heart tissue in fetuses with neonatal lupus erythematosus, improved survival and decreased dilated cardiomyopathy.

• August 25, 2022

In this study, researchers explored the need for antibiotic prophylaxis to prevent urinary tract infections after pyeloplasties

• Surgery
• August 24, 2022

In this study, researchers share key lessons learned from a specialized care team’s proactive and systematic approach to bowl management in patients with spina bifida and spinal cord injury.

• Gastroenterology and GI Surgery
• August 23, 2022

In this study, researchers from the Gastrointestinal Eosinophilic Diseases Program in the Digestive Health Institute sought to characterize eosinophils by subgroup, using the expression of CD11c as a framework.

• Orthopedics and Orthopedic Surgery
• July 26, 2022

After a concussion, athletes cleared to return to play have experienced persistent deficits in neuromuscular control, but an eight-week neuromuscular training intervention for post-concussion could reduce rates of reinjury.

• Surgery
• July 25, 2022

Kasai hepatoportoenterostomy is the standard of care for children with biliary atresia to help relieve the bile duct blockage. Many children may still require a liver transplant. In this study, researchers compared the benefits of the Kasai procedure versus receiving a primary liver transplant.

• Gastroenterology and GI Surgery
• June 24, 2022

A study of pediatric liver transplants during the COVID-19 pandemic found declining rates of transplantation likely due to ethical concerns, logistical challenges, fewer waitlist additions and racial and ethnic disparities.

• Maternal and Fetal Medicine
• June 23, 2022

Offspring of obese macaque mothers fed a Western-style diet had increased periportal fibrosis, indicating that fibrogenesis begins in utero and persists

• Maternal and Fetal Medicine
• June 23, 2022

A Colorado Fetal Care Center study found greater survival among infants with severe congenital diaphragmatic hernia when they receive early intervention with ECMO from high-volume medical centers with a protocoled care approach.