Research background: OSA in those with severe obesity and their response to MBS
- 54% of adolescents with severe obesity in study had obstructive sleep apnea (OSA) before metabolic bariatric surgery (MBS)
- 43% of these patients had severe OSA
- About 2/3 of study patients who had sleep study after MBS had OSA remission
Obstructive sleep apnea can occur in individuals with obesity, and its severity increases with their body mass index. The condition can lead to increased risk for cardiovascular and metabolic disease and death.
Metabolic bariatric surgery (MBS) can improve OSA in some adults with severe obesity, but 50% may still have OSA even after losing significant weight. Little is known about what factors contribute to the health outcomes of adolescents with severe obesity after MBS, including remission of OSA.
Researchers in the Bariatric Surgery Center at Children’s Hospital Colorado sought to (1) identify the occurrence of OSA in patients with severe obesity before and after MBS, and (2) examine factors that were associated with remission of OSA in this patient population.
Research methods: examining OSA severity in adolescents with severe obesity before and after MBS
Researchers retrospectively reviewed the charts of 81 adolescent and young adults before MBS with OSA assessments completed between June 2017 and September 2020 at Children’s Colorado. BMI data was collected before the surgery and at two weeks, four to six weeks, and three, six, nine and 12 months after surgery.
In addition to other pre-surgical evaluations, Children’s Colorado requires a sleep evaluation and sleep studies for any patient with known OSA. Polysomnography (PSG) variables were applied to adult Obstructive Apnea–Hypopnea Index (OAHI) severity scores before and after surgery to establish a baseline for the study.