Children's Hospital Colorado

Second Opinions for Cancer and Blood Disorders

The Center for Cancer and Blood Disorders

Our top-ranked hematology, oncology, blood and marrow transplant and cellular therapy programs are national leaders in new and advanced treatments for pediatric cancers and blood diseases.

Best Children's Hospital by U.S. News & World Report Cancer 2021-2 Badge

Whether your family is looking for help with your child’s existing cancer or blood disorder diagnosis, or you’re still looking for answers, Children’s Hospital Colorado can help. Our experts provide an in-person second opinion that will give you peace of mind and help ensure your child receives the best care available.

What is a second opinion?

A second opinion allows our world-class specialists to review your child’s diagnosis or treatment plan. We collect your child’s health history in an initial phone call.

Then, your family has an in-person appointment with one of our doctors, who reviews your child’s medical records and examines them in person. We give you a thorough assessment of your child’s condition, including treatment recommendations.

Why you should get a second opinion for your child

Medical knowledge and treatments are advancing every day, so it can be particularly helpful to seek guidance from more than one doctor or hospital before starting treatment. This is especially true when the diagnosis is rare or complex — or when the treatment could be life-changing.

A second opinion about your child’s condition can help you:

  • Determine, confirm or clarify a diagnosis
  • Discuss treatment options and compare the risks, benefits and results of these options
  • Understand why symptoms persist despite treatment
  • Find and evaluate new or advanced therapies
  • Consider opportunities to join clinical trials

Why request a second opinion from Children’s Colorado?

Children’s Colorado has consistently been ranked among the best cancer treatment centers in the country. Our Center for Cancer and Blood Disorders provides advanced oncology, hematology, blood and marrow transplant and cellular therapy care for babies, children and teens. Our experts are recognized as global leaders in their specialties and often participate in expert consults and presentations.

Having access to the best cancer and blood disorder treatments means having access to clinical trials. As a leading research center, our doctors and principal investigators are engaged in more than 400 clinical trials across the globe — the most of any pediatric cancer center in the region.

When should I ask for a second opinion?

We’re here to provide clarity if you have questions or feel uncertain about a known or potential cancer or blood disorder diagnosis. A second opinion can be helpful after diagnosis and before treatment, so you can feel confident about your child’s treatment plan. You might also want a second opinion if you’re seeking answers about your child’s symptoms.

Children’s Colorado specialists can provide second opinions for numerous questions related to pediatric cancer and blood disorders. Our areas of expertise include:

  • Pediatric Oncology: With decades of experience, our providers have built one of the nation’s best pediatric oncology centers specializing in the diagnosis, treatment and prevention of childhood cancer.
  • Hematology: Our Hematology Program is internationally recognized for its expertise in diagnosing and treating blood and clotting disorders.
  • Blood and Marrow Transplant and Cellular Therapy: We perform the most bone marrow transplants in our region and offer some of the most advanced cellular therapy options available. And we consistently meet or exceed international standards for bone marrow transplant survival.
  • Hemophilia and Thrombosis Center: Your family has access to one of the world’s premier programs for treating bleeding and clotting conditions in children through our partnership with the University of Colorado Hemophilia and Thrombosis Center.
  • Neuro-Oncology: Our neuro-oncology program is one of the largest in the country, offering the most effective, proven treatments for children with brain or spinal cord tumors, as well as access to the most advanced therapies through research.

What to expect from a second opinion at the Center for Cancer and Blood Disorders

  • First, schedule an initial phone call with our Center for Cancer and Blood Disorders via MyChart. This call will take 15 to 30 minutes and is free of charge.
  • During the call, a friendly team member will collect basic information about your child. We’ll ask a series of questions to help us choose which program(s) and provider(s) we recommend for your in-person visit.
  • If you decide to proceed with an in-person appointment, we’ll help coordinate the details for getting medical records, and discuss insurance or self-pay options ahead of your visit. We’ll also help you schedule an in-person appointment at a convenient time.
    • If your child needs procedures or tests, we’ll help you coordinate the details before your in-person visit.
    • We’ll also help you navigate logistics including lodging options, transportation, parking and local restaurants.
  • At your visit, we’ll provide a comprehensive review of your child’s care and symptoms, and you’ll have the chance to ask the doctor any questions. Our team will provide their expert opinion for your child’s care options and give you all the information you need to make an informed decision.

What should I prepare for my second opinion call?

More information helps our experts provide an accurate diagnosis and makes our process more seamless. Before your second opinion call, please send the following records to

  • Patient Summary
  • Recent and relevant lab test results, if applicable
  • Radiology notes
  • Operative notes, if applicable
  • Pathology reports, if applicable
  • Molecular tumor testing, if applicable
  • Chemotherapeutic treatment regimens with approximate dates, if applicable
  • Radiation therapeutic summary, if applicable
  • MRI scans

As the doctor reviews your case we may need additional records, images and scan results.

Request a second opinion

Ready to get started? Call us or schedule a time for your initial call now:

Second opinions for high-risk leukemia

Some forms of leukemia are harder to treat because they don’t respond quickly to treatment (refractory leukemia), come back after treatment (relapsed or recurrent leukemia) or have certain genetic factors. We offer expert consultation and the most advanced treatments for these high-risk leukemias.

Review of these types of high-risk leukemia issues may require prompt evaluation. For these questions please email us at rather than scheduling a second opinion call.

Frequently asked questions

We’re here to help you find answers and get advice about your child’s health. Expand the windows below for additional information and answers to FAQs about second opinions at the Center for Cancer and Blood Disorders.

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Incredibly different care

At Children’s Colorado, we know kids are incredibly different, from their growing bodies to their developing minds. That’s why they need incredibly different care.

Learn how kids and our care are different