Children's Hospital Colorado

Neurology and Neurosurgery Research at the Neuroscience Institute

We are dedicated to discovering the best ways to diagnose, treat and cure children with neurological disorders. Our doctors and scientists are internationally recognized leaders in their research fields. Their broad range of specialties include epilepsy, neurogenetics, neuromuscular disease/muscle disorders, neuro-oncology, craniopharyngioma, pediatric and neonatal stroke, hydrocephalus and spina bifida.

Research article

Focal cortical dysplasia is a common cause of treatment-resistant epilepsy in children. At Children's Hospital Colorado, however, researchers are homing in on focal cortical dysplasia treatment.

Clinical trial

The goal of the study is to identify biologically rational therapeutics for the medical treatment of adamantinomatous craniopharyngioma by confirming the overexpression of specific molecules and ultimately improving treatment for patients with this rare tumor.

Patients with the diagnosis or clinical suspicion of craniopharyngioma in whom planned clinical management will include tissue sampling
0-21 years of age

Neurology and neurosurgery advancements

Our neurology and neurosurgery specialists have 100+ research studies, one-third of which are industry sponsored clinical trials. Our faculty have also been awarded grant funding by the National Institutes of Health (NIH), Pediatric Epilepsy Research Foundation, the Patient-Centered Outcomes Research Institute (PCORI), among others.

A few of our significant advancements include:

  • Kelly Knupp, MD, co-authored a study in JAMA Pediatrics on the comparative effectiveness of two drugs in the management of infantile epilepsy. The study found a possible benefit to changing traditional drug therapy strategies. These findings are leading to clinical trials and further investigation into medications used in this population.
  • Julie Parsons, MD, participates in several clinical trials that continue to explore new types of life-saving treatments for spinal muscular atrophy. She is also part of a multicenter, longitudinal study to define the natural history of infantile spinal muscular atrophy to aid in future clinical trials and investigations into the management and treatment of the condition.

"We're the only consortium in North America doing work like this."
Todd Hankinson, MD

What our neurology and neurosurgery research means for kids

Our team is committed to improving the lives of children with neurologic conditions and their families. That's why we're researching both common and rare neurological disorders and partnering with leading organizations throughout the world to improve our understanding and treatment of these disorders.

Our partnerships and consortiums include:

Learn more about the Neuroscience Institute.

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