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Restless Leg Syndrome (RLS) is a condition that causes a strong urge to move the legs. This urge to move may be accompanied by other uncomfortable sensations felt inside the legs that are difficult for children to describe. The uncomfortable sensation and urge to move are made worse by rest or lying down and are temporarily relieved by walking or moving the legs.
Periodic Limb Movement Disorder (PLMD) is periodic episodes of repetitive limb movements that occur during sleep. Periodic limb movements in sleep (PLMS) are brief jerks of the foot or leg, typically every 20 to 40 seconds. They can be identified during a sleep study known as polysomnography. PLMD is often associated with RLS but can occur by itself.
In some cases, a gene causes this problem. So, it’s common for another family member to have RLS.
An important chemical in the brain that helps control motion called dopamine may be low in children with both RLS and PLMD. Children with early-onset RLS may show evidence of an iron deficiency in the brain. Iron is required for proper dopamine activity in the nervous system.
RLS symptoms often begin during childhood or adolescence. About 35% of patients report RLS before age 20, and 10% tell doctors that their symptoms appeared by age 10.
Children and adults with RLS or PLMD commonly have disturbed sleep because of the condition. In children, sleep disturbance may occur before they complain of leg discomfort. The quality and quantity of a child’s sleep are often decreased, resulting in moodiness, irritability, inattentiveness, fatigue or hyperactivity.
Children with RLS tend to seek relief from their discomfort by moving their legs often by fidgeting, stretching, walking, running, rocking or changing position in bed. Parents or healthcare providers may mistakenly attribute the child’s discomfort to "growing pains." At school, a child’s attempts to relieve the uncomfortable feelings of RLS may be perceived by teachers as inattentiveness, hyperactivity or disruptive behavior. Because of this, children with RLS may mistakenly be diagnosed with attention deficit hyperactivity disorder.
Restless legs syndrome is a real medical condition that calls for proper evaluation, diagnosis and treatment. Some children with RLS complain of the sensations more during the day than at night.
Doctors often order a blood test to measure iron (serum ferritin) levels for patients who may have RLS. Studies have found associations between low stores of iron in the body and increased RLS symptoms, probably because of iron’s important role in brain dopamine function.
Similarly, iron deficiency can cause or worsen RLS in children and adolescents, even when the deficiency is not severe enough to cause anemia. A ferritin level of less than 50 mcg/L, which may even be in the low-normal range, indicates a potential problem.
A diagnosis of PLMD is based on three criteria:
In a child with RLS, the physical exam is usually normal. Family history is important because there is a 50% chance of passing the RLS trait on to children if a parent has RLS.
Medical professionals have developed criteria for diagnosing RLS in children ages 2 through 12 years. with definite, probable or possible RLS:
Possible RLS: The child has PLMD and a biological parent or sibling has definite RLS, but the child does not meet the criteria for definite or probable childhood RLS.
Adolescents (13 years and older) are evaluated with the adult criteria.
Patients with RLS or PLMD are treated with a combination of learning new behavioral skills, vitamin supplements and other medication.
At Children’s Colorado, our Pediatric Sleep Clinic team is made up of experts in treating children with restless leg syndrome (RLS) and periodic limb movement disorder (PLMD). Our clinicians have years of experience diagnosing and treating these movement disorders. Our sleep psychologist can help families learn good sleep habits to support any medical treatments recommended by our sleep doctors.
The Sleep Team often coordinates care with other specialists and primary care physicians involved in each family’s treatment. Most importantly, our caring staff members are willing to listen to families and “go the extra mile” to improve sleep and optimize development.
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