Children's Hospital Colorado

Crouzon Syndrome

What is Crouzon syndrome?

Crouzon syndrome, also known as craniofacial dysostosis, is a condition characterized by abnormalities of the skull and midface. Patients with Crouzon syndrome may also have hearing loss or cleft palate. Individuals with Crouzon syndrome with acanthosis nigricans may develop dark velvety skin changes on the neck and armpits.

Who gets Crouzon syndrome?

Crouzon syndrome is a rare congenital condition that occurs in 1 of 25,000 newborn babies in a 1:1 male to female ratio. It may be inherited in an autosomal dominant fashion from a parent with Crouzon syndrome, or be due to a fresh genetic mutation in the fibroblast growth factor receptor 2 gene (FGFR2) or, less frequently, the FGFR3 gene. A parent with Crouzon syndrome has a 50% chance of passing the condition to a child.

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Karisa Reynolds, PA

Karisa Reynolds, PA

Physician Assistant

Thomas Inge, MD

Thomas Inge, MD

Surgery - Pediatric, Surgery

Jessica Keester, NP

Jessica Keester, NP

Certified Pediatric Nurse Practitioner

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John Bealer, MD

John Bealer, MD

Surgery - Pediatric, Surgery