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Colorado Fetal Care Center

Agenesis of the Corpus Callosum

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What is agenesis of the corpus callosum? 

Agenesis of the corpus callosum is a rare brain condition that is present at birth. It occurs when the corpus callosum, the band of nerve fibers connecting the left and right sides of the brain, doesn’t develop properly.  

This irregular development can result from: 

  • Poorly formed fibers (dysgenesis of the corpus callosum) 
  • No fibers at all (absent corpus callosum) 
  • Too few nerve fibers (partial agenesis of the corpus callosum)  

Some cases of agenesis of the corpus callosum tend to cause few to no symptoms. In other cases, your child may need long-term medical care to manage physical and developmental differences.  

Finding agenesis of the corpus callosum early can help ensure your child receives specialty care, including neurology, neonatology, physical therapy and occupational therapy to help their growth and development.    

What causes agenesis of the corpus callosum? 

We can’t always find the cause of agenesis of the corpus callosum, but it may be connected to:  

  • Changes in fetal brain development 
  • Fetal alcohol syndrome 
  • Fetal brain infection or injury 
  • Genetic changes  

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