My research interests are focused on identifying why some children with single ventricle heart disease do well with surgical palliation while others are prone to heart failure. Increasing our understanding of heart failure in this population is essential to improving outcomes for the future.
For Referring Providers:
My research interests focus on elucidating the molecular mechanisms underlying pediatric single ventricle heart failure with the goal of discovering novel pediatric-specific therapeutic targets. Currently, my projects include: 1) determining the molecular and functional myocardial effects of phosphodiesterase 1 inhibition in the failing single ventricle, and 2) identifying circulating miRNAs that may represent biomarkers of single ventricle heart failure.