How is nephrotoxicity treated?
Nephrotoxicity treatment depends on its apparent cause and severity. Milder cases may only require removal of the suspected chemical or medication causing the problem. In some cases, nephrotoxic drugs may need to be continued if they are essential for a patient’s successful care, even though they may be harming the kidney (chemotherapy, for example).
If there is a lot of kidney inflammation that is attributed to nephrotoxicity, which we could tell from a biopsy, we might suggest a course of steroid treatment to reduce the inflammation. If either acute kidney injury (AKI) or chronic kidney disease (CKD) due to nephrotoxicity are severe enough, we may suggest kidney dialysis to substitute kidney function. If irreversible, advanced CKD has developed, we may discuss kidney transplantation and make a referral for an evaluation.
Why choose us for treatment of nephrotoxicity?
Nephrotoxicity can require a broad range of highly specialized multidisciplinary care. For children, this range of care is available at Children’s Colorado, with its pediatric Kidney Care team and all the other pediatric services that may need to be involved, such as our pediatric Department of Pharmacy.
Depending on the type and severity of the nephrotoxicity, we may need to conduct thorough assessments through different departments to identify what medication may be responsible for a child’s nephrotoxicity and whether this medication can be stopped. If your child does require dialysis or kidney transplantation, we are well-equipped to handle both. Children’s Colorado offers the only child-specific dialysis and transplant programs in the region, with outstanding outcomes compared to the national average.