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Children’s Hospital Colorado
Anschutz Medical Campus
13123 East 16th Avenue
Aurora, CO 80045

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Cancer and Blood Disorders

Daniel Ambruso, MD

Associate Medical Director, Belle Bonfils Memorial Blood Center
Director, Research Belle Bonfils Memorial Blood Center

Specialties:: Hematology/Oncology - Pediatric , Pediatrics
Conditions:: Blood Disorders, Bleeding Disorders

Request An Appointment 720-777-6740

Get to know his background

Clinical interests

I am interested in Qualitative and Quantitative Disorders of Neutrophils, Allo and Autoimmune Disorders of Red Cells and Platelets, General Hematology and Transfusion Medicine. Additionally, I have focused on the establishment of a Cord Blood Bank and the Bonfils Cord Blood Services at Bonfils Blood Center, which provides Stem Cells for Hematopoietic Stem Cell Transplantation.

Education and fellowships

Undergraduate 1969

Georgetown University (DC)

Medical School 1973

University of Rochester School of Medicine and Dentistry

Residency 1976

Case Western Reserve University (MetroHealth) Program, Pediatrics

Fellowship 1978

University of Colorado, Pediatric Hematology / Oncology

Fellowship 1979

National Jewish Medical and Research Center, Allergy and Immunology

Location and affiliations

Anschutz Medical Campus, Aurora

13123 East 16th Avenue
Aurora, CO 80045

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Research and grants

Website: http://www.ncbi.nlm.nih.gov/pubmed?term="Ambruso DR"[Author]

For Patients:
I am interested in Neutrophil Function in the Following Clinical Groups: Thermal Injury and Trauma Patients; Newborn Patients; Patients with Absence of Specific Granules; Patients with Glycogenosis lb; and Patients with Chronic Granulomatous Disease. I, also, focus on Chronic Transfusion Therapy and Iron Overload in Patients with Chronic Anemia. Additionally, I am interested in Antibody-Mediated Disorders of Platelets and Neutrophils, as well as the Generation of Lysophosphatidylcholines in Stored Blood Components and their relationship to the Pathophysiology of Transfusion Related Acute Lung Injury (TRALI).

For Referring Providers:
I am interested in the Respiratory Burst Activity and Bactericidal Activity of Neutrophils and Monocytes. Additionally, I focus on the Priming Mechanisms of Neutrophil Oxidase and the Development of Clinical Models of Excess Inflammation. I, also, concentrate on Blood Component Storage and Pathogen Reduction, as well as the Counting of Residual Leukocytes in Leukoreduced Blood Components. I collaborate with COBE BCT to develop new equipment and systems to separate platelets from whole blood. Additionally, I am interested in Alloimmunization in Response to Red Cell and Platelet Transfusions.