Children's Hospital Colorado

Heart Research

Dr. Dunbar Ivy Listens to a toddler's heart while the child plays with a toy car.
Research article

Dr. Dunbar Ivy is part of a select group of PH experts on the forefront of clinical trials, research and treatment.


At Children’s Hospital Colorado, we believe that every child deserves to have a happy, healthy future. That’s why cardiac research is so important to improving the outcomes for children with heart conditions. Research is also a key part of our hospital’s mission.

A team of researchers working towards healthier hearts

The Heart Institute includes a team of clinical and basic science researchers focused on improving the understanding and treatment of heart disease. Here are some highlights of our team’s innovative work and research projects:

  • Our interventional cardiologists were among the first to use minimally invasive heart catheters to reach and repair heart defects in children.
  • Our pulmonary hypertension (PH) researchers are conducting a five-year study to improve the diagnosis and treatment of PH in children. This study uses 200 patient-specific computer models created to mimic blood flow and biomechanics of the pulmonary system of infants and children.
  • Our surgeons are involved in studies to determine the best surgical techniques to minimize the adverse effects of cardiac surgery and maximize the long-term benefit to children and adults.
  • Our organ and heart transplant research has led to new ways of using the immune system to reduce the likelihood of the body rejecting a transplanted heart.

In total, there are more than 100 different research studies going on at our Heart Institute – all designed to improve the health and well-being of your child.

Learn more about our doctors’ research work at the University of Colorado School of Medicine.

A national leader in congenital heart disease research

The Heart Institute at Children’s Colorado is also part of the National Pediatric Cardiology Quality Improvement Collaborative, an initiative to improve outcomes for kids with congenital heart disease. This allows us to work with many other national pediatric cardiology and cardiac surgery centers to share information and improve the quality of life for kids with single ventricle cardiac anatomy.

See why our outcomes make us one of the top heart hospitals
Jaden Senn shows off the "tough guy" scar from his Fontan operation.

Fontan procedure innovation at the Single Ventricle Clinic

Children who undergo the Fontan procedure often outgrow the materials used in reconstructive surgeries. But regenerative medicine may change that.