Children's Hospital Colorado

Research at the Heart Institute

At Children's Hospital Colorado, we believe every child deserves a happy, healthy future. Child health research and innovation are at the core of our commitment to deliver the best clinical care for kids. With each patient we see in the Heart Institute, our physicians and caregivers seek to improve outcomes and deliver world-class care. 

Research Article

Researchers at Children's Hospital Colorado's Pediatric Heart Institute are utilizing big data to speed up discovery. By adopting business world techniques, the researchers apply a data-driven, inductive approach, using blood tests to measure biomarkers and machine learning to sort the data, leading to the development of new research questions and speeding up the discovery process.

Clinical Trial

Researchers at Children’s Hospital Colorado are investigating the safety and feasibility of providing regenerative therapy for a rare congenital heart defect called hypoplastic left heart syndrome (HLHS).

Infants diagnosed with hypoplastic left heart syndrome in utero
Stem cell collection at birth; Glenn procedure at 3-6 months old

Cardiology and heart surgery advancements

Portrait image of Dr. Miyamoto
"Kids deserve focused study. We shouldn’t just rely on what is known to occur in adults; you have to study children just as carefully, just as intensely, as you study adult disease."
Shelley Miyamoto, MD

What our heart research means for kids

The Heart Institute is actively engaged in research to determine the best ways to care for children with congenital or acquired heart disease. There are approximately 80 research studies occurring within the Heart Institute with more than half that are actively enrolling. These studies range from examining cells in the heart to clinical trials of new medications or devices used to treat heart problems in kids. 

Funding for the Heart Institute research portfolio comes from many different sources. These sources include grants from the National Institutes of Health, American Heart Association, Additional Ventures, Department of Defense and other research foundations, industry departments, internal awards and from the department itself. The Heart Institute is eternally thankful for all the children and families who choose to participate in research. Without them, we would not be able to learn the best ways to take care of kids with congenital or acquired heart disease. 

Stay informed

Get the latest updates on Twitter

Advancements in pediatric research, clinical innovation and news Follow Us